Abstract

Introduction: Despite significant advancements in the field of psychiatry over the decades, issues related to the management of certain mental health conditions, such as anxiety, stress, and intellectual disabilities, continues to be a mystery. Mental disorders are increasingly prevalent globally, necessitating innovative and holistic treatment strategies. Traditional Ayurvedic medicine, particularly Panchakarma therapies, offers a comprehensive approach to mental health through detoxification and balance restoration. This review aims to investigate the role of Panchakarma in treating mental disorders. Methods: A systematic review of literature was conducted, sourcing studies from databases such as PubMed, Google Scholar, and Ayurvedic journals published between 2000 and 2024. Keywords included “Panchakarma,” “detoxification,” “mental disorders,” and “Ayurveda.” Data were synthesized to evaluate the efficacy, mechanisms, and patient outcomes associated with Panchakarma therapies. Results: The findings suggest that Panchakarma therapies, including Vamana (therapeutic vomiting), Virechana (purgation), and Basti (enema) and shirodhara, Nasya also significantly contribute to alleviating symptoms of anxiety, depression, and stress-related disorders. Bio-purification through these methods appears to restore physiological balance, improving psychological well-being. Additionally, studies highlight the reduction of oxidative stress and inflammation, which may correlate with symptom improvement. Discussion: The review emphasizes the importance of holistic approaches in mental health treatment, advocating for integration of Ayurvedic practices within conventional psychiatric care. It discusses the need for further clinical trials to elucidate the neurobiological underpinnings of these therapies and their long-term benefits. Conclusion: Panchakarma therapies represent a promising avenue for detoxification and management of mental disorders, warranting further research to validate their efficacy and to explore the mechanisms involved. As public interest in alternative therapies grows, integrating these traditional practices could enhance mental health outcomes. KEY-WORDS: Manasroga, Panchkarma, mental disorders