Pain (Ruja) is a major clinical symptom of many diseases affecting quality of life.  Pain can be described as any physical or mental suffering or discomfort caused by illness or injury. No matter however mild the pain is anywhere in the body it lands person in state of discomfort and affects day to day activities. Pain can present in various ways as throbbing pain in toothache, colic pain which comes in spasm as in renal calculi, muscular pain as in sprain, sport injury and joint pain due to inflammatory condition and many more. According to modern review today’s era musculoskeletal and neuromuscular pain like pain of arthritis, sciatica, lumber spondylosis, migraine, etc are very common. Pain is also categorized as acute or chronic on the basis of duration. Our answer to pain is pain-killer medicines, which on frequent uses kills our resistance power.  Aims and objectives: To study the Ayurvedic basis of acute pain management and review the classical texts and synthesize the role of Agnikarma procedure in acute pain management. Materials and Methods: Relevant Ayurvedic and Modern literature is the material of the paper. Ayurveda explains the origin of pain due to vitiated Vata dosha and once Vata dosha is treated efficiently, the pain subsides automatically. Many people have a false belief that Ayurveda is not good in curing acute pain and Ayurvedic medicines should only be consumed in chronic pain and it always give very slow result but the thing is they are unaware of the wonderful management of Ayurveda. To relieve this pain every person seeks such a treatment which has minimum side effects and maximum benefits. Discussion: Ayurveda para surgical procedure Agnikarma can also be useful in acute pain conditions. Conclusion: Here it may be concluded that Agnikarma a para-surgical procedure involving therapeutic application of controlled heat, is described in Ayurveda as an effective modality for immediate pain relief.