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ISSN: 2583-3677

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Review Article

Year: 2024 |Volume: 3 | Issue: 01 |Pages: 32-37


About Author

Danga S.K.1 , Danga Shubhangi.2

1Professor & Head, Dept. of Kayachikitsa, Jupiter Ayurved Medical College, Nagpur.

2Assistant Professor, Dept. of Sanskrit Samhita Sidhhant, B.M. Ayurved Mahavidyalaya, Nagpur.

Correspondence Address:

Danga S.K. Professor & Head, Dept. of Kayachikitsa Jupiter Ayurved Medical College, Nagpur. Email:

Date of Acceptance: 2024-02-27

Date of Publication:2024-04-15


Source of Support: Nill

Conflict of Interest: None declared

How To Cite This Article: Danga S.K., Danga Shubhangi. Drug Efficacy of Khadiradi kashaya for Purishaj krimi. (Worm Infestation). AYUSCRIPT 2024;3(1):32-38 DOI:


There are two types of Krimi existing in human body– Sahaj & Vaikarik Krimi. Among them, Vaikarik Krimi is causative factor for disease in human being. It is said that Krimi may be one cause for Kushtha, Pandu, Grahani, and Karshyata. Purishaja Krumi means "krumi born in the stools, which desire to migrate in the body from one organ or system to another, that which has the capacity to penetrate from one tissue to another and which gets nourishment from mansa." In this era of fast-food people are lacking in awareness about nutrition and intake of diet, dietary habit due to this many patients remains as it is or without diagnosis. Aim of study is to see the efficacy of Khadiradi Kashaya – oral drug in Purishaj krimi (worm infestation). Khadiradi kashaya could be an alternate choice Antihelminthic drugs in the management of Purishaj krimi; it has potential to cure the disease and having potential to cure symptoms like vidbheda, shool, agnisada and jwar of Purishaj krimi. Khadiradi Kashaya described in Yogratnakar having utility in the management of Purishaj krimi.

KEY-WORDS: Purishaj krimi, Kushtha, Pandu, Grahani, Karshyata


Intestinal worm infestation is one of the major concerns in childhood health problems in developing countries. In Ayurveda, various types, diagnosis & management of Krimiroga described in detail in all Samhitas. By etymology, Krumi may be defined as the one which causes sufferings.1 In Vedas also references have been cited regarding Krimi. In human body there are two types of KrimiSahaj & Vaikarik Krimi.(Charak Viman sthan7/9) Among them Vaikarik Krimi are harmful to human being. It is thought to considered that Krumi is one of the causes for Kushtha, Pandu, Grahani, Karshyata. Children are more sufferer comparison to adult.2 Since worms are normally found in all human beings, mostly they are asymptomatic, symptoms observed with a few worms living inside the intestines.

Krimi Samanya Chikitsa: Acharya Charaka has narrated the basic principle in the treatment of Krimi in the Vyadhita rupiya adhyaya of Vimana Sthana.3 Consecutive adoption of the three methods of treatment has been stated which are-Apakarshana, Prakruti Vighata and Nidana Parivarjana.4

Acharyas Charaka,5 Sushruta6, Vagbhata7 and other Acharyas have given a systematic description of Krimi rogas including their classification, causative factors, signs and symptoms and treatment.


Since kled and ama serve as the building blocks for Krumi Utpatti, their presence in excess or greater amounts in the human body increases the likelihood of agnimandya and Purishaja Krumi's development. The primary causes of purishaj krumi are thought to be Masha, Gud, Pishtmma, Til, Sngidha, and sheet ahar, Lavana rasatmak ahar, Anoop mansa, Madhura rasatmak ahar, Kusumbha sneh, Viruddha ahar, Avyayam, Paryushit ahar, Divaswap, and Asatmya ahar.

Eating outside food like fast food, bakery product, eating vada pav, samosa, pav bhaji, eating non veg foods, the properties of these food items are ushna, tikshna, vidahi, and guru (heavy for digestion). Madhura ras is heavy for digestion because it is having pruthvi and jala mahabhuta pradhan. This leads to aggravation of Kapha, which causes agnimandya. These give rise to kshudhamandya, thus aggravating amotpatti and ultimately resulting in excess kled utpatti which results into krumi in the stomach and intestine.

Khadiradi Kashaya:

Khadiradi Kashaya having drug like Khadir, Kutaj, Nimba, Vacha, Nishottar, Amalaki, Haritaki, Bibhitak, Shunthi, Marich, Pippali and Gomutra having properties like krimighna, kandughna, drug like Khadir, Kutaj, Nimba, Vacha and Nishottar having laxative property while Triphla & Trikatu has deepan as well as pachan property. Gomutra has lekhan and sara property. Overall this formula was dominantly having katu ,tikta and kashaya rasatmak guna and having tikshna guna along with ushna virya which results in destruction of samprati of Purishaj krimi.10Cow urine, or gomutra, is described in Ayurvedic literature such as the Sushruta Samhita, Ashtanga Sangrah, and Bhav Prakash Nighantu as an excellent medicinal material or secretion of animal origin with numerous therapeutic purposes. In India, cows, or Kamadhenu, are revered as sacred animals.11 Numerous studies have demonstrated the antimicrobial activity of CU from native and hybrid breeds against a variety of pathogens, including Salmonella typhi, E. coli, Proteus vulgaris, S. aureus, Bacillus cereus, Staphylococcus epidermidis, Klebsiella pneumonia, Pseudomonas aeruginosa, Pseudomonas fragi, Streptococcus agalactiae, Enterobacter aerogenes, Aeromonas hydrophila, Micrococcus luteus, Streptococcus pyogenes, Streptomyces aureofaciens, Lactobacillus acidophilus and Bacillus subtilis, and Leishmania donovani.12,13,14.


Khadiradi Kashaya is wonderful drug used for Worm infestation (Krimi) and it is found to be useful in many research studies and observed very effective in reducing signs and symptoms of Purishaj krimi.


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