Correspondence Address:
Dr. Kshitiza Airi Lecturer, Department of Kriya Sharir, Govt. Ayurvedic College and Hospital, Patiala, Punjab. Email: tinny.airi@gmail.com , Mobile No.: 7087422800
Date of Acceptance: 2025-06-27
Date of Publication:2025-04-17
Article-ID:AYU_149_10_25 https://ayuscript.com
Source of Support: Nil
Conflict of Interest: Non declared
How To Cite This Article: Airi K. Pathak A. Pathogenesis of Mutraghata and Mutrashmari & its preventive Management. AYUSCRIPT 2025;4(2):69-75 DOI: http://doi.org/10.55552/AYUSCRIPT.2025.4209
Mutraghata (urinary retention) and Mutrashmari (urolithiasis) are significant conditions of the urinary system extensively discussed in Ayurvedic literature. Mutraghat is characterized by difficulty in urination caused by obstruction or dysfunction in the urinary tract, predominantly linked to aggravated Vata dosha. Mutrashmari refers to stone formation due to imbalances in Kapha, Pitta, and Vata doshas, paralleling modern urolithiasis, which involves crystal formation from supersaturation of urinary solutes. Globally, urolithiasis affects 10% of men and 5% of women, with an increased prevalence in regions with hot climates due to dehydration and dietary habits. India reports over a million cases annually, emphasizing the relevance of both preventive and therapeutic approaches. Pathophysiologically, Mutraghat involves the obstruction of urine flow due to structural, inflammatory, or dosha-related factors, while Mutrashmari results from Kapha consolidating with Pitta and Vata doshas to form calculi. Modern medicine offers advanced surgical and non-invasive techniques such as extracorporeal shock wave lithotripsy (ESWL) and ureteroscopy for stone removal, along with lifestyle modifications to prevent recurrence. Ayurvedic management emphasizes the use of mutravirechaniya (diuretics) and ashmarighna (lithotriptic) herbs such as Gokshura, Varuna, and Pashanabheda. Panchakarma therapies, including Basti and Uttar Basti, are integral for dosha pacification and functional restoration. It concludes by highlighting the need for integrating Ayurvedic and modern medical practices to address these disorders comprehensively, particularly in recurrent or chronic cases.
Key words: Mutraghata, Mutrashmari, Pathophysiologically, Mutraghat, mutravirechaniya, ashmarighna (lithotriptic), Gokshura, Pashanabheda.
Ayurvedic literature extensively discusses urinary disorders, particularly Mutraghat and Mutrashmari, as part of the broader spectrum of diseases involving the Mutravaha Srotas (urinary system). Sushruta Samhita classifies Mutrashmari among the "Ashta Mahagada" (eight grave disorders) due to its potential fatality if left untreated. Mutraghat (urinary retention) and Mutrashmari (urolithiasis) have overlapping and distinct features. Mutraghat refers to difficulty in urination caused by obstruction or vitiation in the urinary tract, predominantly driven by Vata dosha aggravation. Mutrashmari refers to the pathological development of stones, primarily due to Kapha dosha, which hardens with the involvement of Pitta and Vata doshas. From an epidemiological perspective, urolithiasis affects approximately 10% of men and 5% of women globally, with higher prevalence rates in regions with hot and dry climates. In India, over one million cases are reported annually, with a recurrence rate of 50% within 5–7 years. Men are more commonly affected, particularly in the age group of 30–50 years, although the prevalence is increasing among women due to changing dietary habits and lifestyle factors.
Mutraghata: Mutraghata is primarily a Vataja disorder. Vata dosha, especially Apana Vayu, is responsible for the regulation of urine excretion. Aggravation of Vata due to factors like suppression of natural urges (vegavarodha), dry and unwholesome diets, or excessive physical activity leads to obstruction of urinary flow. Structural changes such as inflammation or narrowing of urinary pathways may also contribute to the condition. Symptoms include abdominal distension, retention of urine, and pain, often indicative of urinary tract obstruction.
Stone formation in Mutrashmari is a consequence of Kapha-dominant pathology. Kapha consolidates with Pitta and Vata doshas, creating crystals that develop into calculi.This process mirrors the supersaturation, nucleation, and aggregation mechanisms described in modern medical urolithiasis research. Contributing factors include poor hydration, sedentary lifestyles, excessive intake of calcium-rich or Kapha-provoking foods, and genetic predispositions.
Modern Medical Approaches
In modern medicine, urolithiasis management includes extracorporeal shock wave lithotripsy (ESWL), ureteroscopy, laparoscopic procedures, and open surgeries. These interventions primarily address the removal of stones and the relief of obstruction.Prevention strategies focus on lifestyle modifications, increased water intake, and dietary changes to reduce recurrence rates.
Classical texts like Charaka Samhita and Sushruta Samhita advocate therapies such as mutravirechaniya (diuretics) and ashmarighna dravyas (lithotriptics). Herbs like Gokshura (Tribulus terrestris), Varuna (Crataeva nurvala), and Pashanabheda (Bergenia ligulata) are commonly used for their diuretic and stone-dissolving properties.Panchakarma therapies like Basti (medicated enemas) and Uttar Basti (urethral instillation) are employed to restore the function of Apana Vayu and eliminate obstruction.
exercises like yoga asanas
(e.g., Vajrasana, Pavanamuktasana) to improve metabolism and prevent stagnation of Kapha.
The pathogenesis of Mutraghat and Mutrashmari aligns with both classical Ayurvedic theories and modern biomedical understanding. Ayurvedic descriptions of stone formation, such as Sushruta's analogy of Kapha solidifying with Pitta and Vata in the bladder, resonate with modern concepts of urolithiasis as a physicochemical process. Clinical studies have shown that Ayurvedic formulations can manage small- to-moderate-sized stones effectively without invasive procedures. A study highlighted the efficacy of Varuna and Gokshura in dissolving stones and improving urinary flow. Panchakarma therapies have also demonstrated benefits in chronic cases of urinary retention, complementing conventional management. However, large-scale clinical trials are needed to establish the safety and efficacy of these therapies in diverse populations. Integration of Ayurvedic and modern medical approaches may offer a holistic solution, particularly in recurrent or chronic cases. Research integrating Ayurvedic principles with modern biomedical studies has started to provide evidence for the efficacy of traditional approaches in managing these conditions. Studies on Ayurvedic herbs and therapies highlight their ability to not only dissolve calculi but also enhance renal function and alleviate symptoms. Large-scale clinical trials and pharmacological investigations into Ayurvedic formulations will further validate their role in urological care. A deeper understanding of the pathophysiology of Mutraghat and Mutrashmari, coupled with innovative research integrating Ayurvedic and modern perspectives, could significantly enhance patient care. By combining the immediate effectiveness of modern medicine with the holistic, preventive, and restorative approaches of Ayurveda, healthcare providers can offer a more comprehensive and patient- centered management strategy. This integration would not only address acute symptoms but also emphasize long-term prevention, thereby improving the overall quality of life for patients.
Mutraghat (urinary retention) and Mutrashmari (urolithiasis) remain significant challenges in the fields of both Ayurvedic and modern urology due to their high prevalence and recurrence rates. These conditions not only impact the quality of life but also pose significant risks of complications such as infections, chronic kidney disease, and severe obstructive uropathy if left untreated. The integration of traditional and modern approaches offers a promising pathway for holistic management and prevention of these disorders. Modern medicine provides advanced diagnostic tools and effective interventions such as extracorporeal shock wave lithotripsy (ESWL), ureteroscopy, laparoscopic procedures, and open surgeries, which have revolutionized the treatment of urolithiasis. These approaches, coupled with pharmacological measures such as potassium citrate and thiazide diuretics for stone prevention, ensure prompt relief and effective management of acute and recurrent cases. However, the invasive nature of these treatments and potential side effects of medications underscores the need for complementary and preventive approaches. Ayurveda, on the other hand, offers a comprehensive framework for both prevention and cure, grounded in its centuries-old principles of Tridosha theory and holistic health. Ayurvedic formulations such as Gokshura (Tribulus terrestris), Varuna (Crataeva nurvala), Pashanabheda (Bergenia ligulata), and Shilajit have been shown to possess diuretic, anti-inflammatory, and lithotriptic properties, aiding in both the dissolution and expulsion of stones. Panchakarma therapies such as Basti and Uttar Basti not only detoxify the urinary system but also restore the natural functioning of Apana Vayu, addressing the root cause of Mutraghat. Dietary and lifestyle modifications, including the use of hydrating, Kapha-pacifying, and alkaline foods, as well as avoidance of suppression of natural urges (vegavarodha), are integral to long-term prevention. Moreover, the integration of Pathya (recommended diet) and Apathya (restricted diet) into daily life plays a pivotal role in reducing recurrence rates and maintaining urinary system health. The emphasis on hydration, avoidance of Kapha-aggravating foods, and the use of natural diuretics ensures that the urinary tract remains clear of obstructions and inflammation. Ayurveda’s preventive focus minimizes the risk of recurrence, making it particularly valuable in chronic or recurrent cases.
Charaka. Chikitsa Sthana. Chapter 26, Verse 37-39. In: Acharya YT, editor. Charaka Samhita. 5th ed. Varanasi: Chaukhamba Sanskrit