Nourishing Mother and Mind: Rasa-Dhatu, Kshaya and Hormonal Imbalance in Postpartum Depression and Lactation Physiology; an integrative Ayurvedic Neuroendocrine Review

Abstract

Background: Postpartum depression (PPD) is a growing concern that affects a mother’s emotional well-being and her ability to bond with her newborn. While modern science links PPD primarily to hormonal changes after childbirth, Ayurvedic thought offers a complementary perspective rooted in the depletion of Rasa Dhatu the body’s primary nourishing tissue. This review brings together both modern neuroendocrine insights and classical Ayurvedic principles to offer a more integrative understanding of the condition. Aim:To examine the role of hormonal fluctuations and Rasa Dhatu depletion in the development of PPD, and to explore how Ayurveda can contribute to a more holistic approach in its prevention and care. Materials and Methods:This narrative review draws upon Ayurvedic classical texts alongside contemporary scientific studies. Key hormones involved in postpartum physiology such as estrogen, progesterone, prolactin, and oxytocin were examined in the context of their influence on mood, lactation, and bonding. Results and Discussion:Postpartum hormonal shifts, especially the sudden drop in estrogen and progesterone, are known to affect mood regulation. Disruptions in prolactin and oxytocin levels impact emotional connection and milk production. These physiological disturbances mirror the classical signs of Rasa Dhatu Kshaya and fatigue, low milk output, emotional vulnerability, and mental dullness. Conclusion: Addressing PPD by emphasizing the nourishment of both body and mind. This integrative lens underscores the importance of early postpartum care that goes beyond symptom management.

Key words: Postpartum Depression; Rasa Dhatu; Rasa Dhatu Kshaya, Manovaha Srotas; Rasayana Therapy.